Skip to main content

Physical Activity, Obesity Status, and Glycemic Control: The ATTICA Study

Physical Activity, Obesity Status, and Glycemic Control: The ATTICA Study

Conclusion: Our data show that physical activity is a significant factor on insulin sensitivity, whereas increased physical activity may ameliorate the well-known effects of obesity on insulin sensitivity

[...]

The basic metabolic abnormality of both diabetes and obesity is resistance of peripheral tissues to the action of insulin. In populations with genetic susceptibility to diabetes, insulin resistance has been characterized as a precursor of diabetes mellitus.[12] Obesity has been considered a major risk factor for the development of non-insulin-dependent diabetes mellitus. In a cohort of nearly 7000 men with no history of diabetes, the risk after a mean follow-up of 12 yr for those with BMI levels of 25.0-27.9 kg·m-2 was more than double that for those with BMI < 25.0 kg·m-2, and it increased further with increasing BMI.[23] In the same study, weight gain during the follow-up period was associated with a substantial increase in the risk of diabetes, whereas weight loss had the opposite effect. Even though obesity-related insulin resistance may never develop to the typical form of diabetes, the condition itself has been recognized as an independent morbidity risk factor, especially for cardiovascular diseases.[18,20]

Epidemiologic evidence suggests that regular physical activity is a key factor in the prevention or treatment of metabolic diseases. Prospective cohort studies have revealed that relatively high physical activity levels are associated with substantial reductions in the risk of developing non-insulin-dependent diabetes mellitus,[9] latent autoimmune diabetes,[2] and coronary heart disease.[21] In addition, extended clinical trials that incorporated a feasible goal of increased physical activity in individuals with impaired glucose tolerance have reported decreases in the risk of developing diabetes by 46-58% after follow-up evaluations of 3-6 yr.[6,11,15,22]

To the best of our knowledge, few data on the relationship between estimates of insulin resistance and physical activity levels have been presented. One study of 5159 middle-aged men has shown an inverse relationship between physical activity and fasting insulin levels, with those individuals performing vigorous activities having the lowest insulin levels, despite no differences in blood glucose levels among category groups of physical activity.[24] The purpose of the present study was to evaluate the relationship between physical activity status, obesity or overweight, and indices of glycemic control and insulin resistance.

Comments

Popular posts from this blog

Insulin Resistance- cause of ADD, diabetes, narcolepsy, etc etc

Insulin Resistance Insulin Resistance Have you been diagnosed with clinical depression? Heart disease? Type II, or adult, diabetes? Narcolepsy? Are you, or do you think you might be, an alcoholic? Do you gain weight around your middle in spite of faithfully dieting? Are you unable to lose weight? Does your child have ADHD? If you have any one of these symptoms, I wrote this article for you. Believe it or not, the same thing can cause all of the above symptoms. I am not a medical professional. I am not a nutritionist. The conclusions I have drawn from my own experience and observations are not rocket science. A diagnosis of clinical depression is as ordinary as the common cold today. Prescriptions for Prozac, Zoloft, Wellbutrin, etc., are written every day. Genuine clinical depression is a very serious condition caused by serotonin levels in the brain. I am not certain, however, that every diagnosis of depression is the real thing. My guess is that about 10 percent of the people taking

Could Narcolepsy be caused by gluten? :: Kitchen Table Hypothesis

Kitchen Table Hypothesis from www.zombieinstitute.net - Heidi's new site It's commonly known that a severe allergy to peanuts can cause death within minutes. What if there were an allergy that were delayed for hours and caused people to fall asleep instead? That is what I believe is happening in people with Narcolepsy. Celiac disease is an allergy to gliadin, a specific gluten protein found in grains such as wheat, barley and rye. In celiac disease the IgA antigliadin antibody is produced after ingestion of gluten. It attacks the gluten, but also mistakenly binds to and creates an immune reaction in the cells of the small intestine causing severe damage. There is another form of gluten intolerance, Dermatitis Herpetiformis, in which the IgA antigliadin bind to proteins in the skin, causing blisters, itching and pain. This can occur without any signs of intestinal damage. Non-celiac gluten sensitivity is a similar autoimmune reaction to gliadin, however it usually involves the

Blue-blocking Glasses To Improve Sleep And ADHD Symptoms Developed

Blue-blocking Glasses To Improve Sleep And ADHD Symptoms Developed Scientists at John Carroll University, working in its Lighting Innovations Institute, have developed an affordable accessory that appears to reduce the symptoms of ADHD. Their discovery also has also been shown to improve sleep patterns among people who have difficulty falling asleep. The John Carroll researchers have created glasses designed to block blue light, therefore altering a person's circadian rhythm, which leads to improvement in ADHD symptoms and sleep disorders. […] How the Glasses Work The individual puts on the glasses a couple of hours ahead of bedtime, advancing the circadian rhythm. The special glasses block the blue rays that cause a delay in the start of the flow of melatonin, the sleep hormone. Normally, melatonin flow doesn't begin until after the individual goes into darkness. Studies indicate that promoting the earlier release of melatonin results in a marked decline of ADHD symptoms. Bett